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Protein Kinase A-Dependent Phosphorylation Modulates β(1)Pix Guanine Nucleotide Exchange Factor Activity through 14-3-3β Binding

β(1)Pix is a guanine nucleotide exchange factor (GEF) for the small GTPases Rac and Cdc42 which has been shown to mediate signaling pathways leading to cytoskeletal reorganization. In the present study, we show that the basal association between endogenous βPix and endogenous 14-3-3β was increased a...

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Detalhes bibliográficos
Main Authors: Chahdi, Ahmed, Sorokin, Andrey
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258773/
https://ncbi.nlm.nih.gov/pubmed/18160719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00898-07
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