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Interaction of ICP34.5 with Beclin 1 Modulates Herpes Simplex Virus Type 1 Pathogenesis through Control of CD4(+) T-Cell Responses

Autophagy is an important component of host innate and adaptive immunity to viruses. It is critical for the degradation of intracellular pathogens and for promoting antigen presentation. Herpes simplex virus type 1 (HSV-1) infection induces an autophagy response, but this response is antagonized by...

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Detalles Bibliográficos
Autores principales: Leib, David A., Alexander, Diane E., Cox, Douglas, Yin, Jiyi, Ferguson, Thomas A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786728/
https://ncbi.nlm.nih.gov/pubmed/19759141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01676-09
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