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Enhanced Pathogenesis of an Attenuated Herpes Simplex Virus for Mice Lacking Stat1

Mice lacking the Stat1 interferon signaling gene were infected with herpes simplex virus type 1 (HSV-1) or an attenuated recombinant lacking virion host shutoff (Δvhs). Δvhs virus-infected Stat1(−/−) mice showed levels of replication equivalent to that of the wild-type virus-infected control mice bu...

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Библиографические подробности
Главные авторы: Pasieka, Tracy Jo, Lu, Betty, Leib, David A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395151/
https://ncbi.nlm.nih.gov/pubmed/18400863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00297-08
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