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Functional Genomics Reveals an Essential and Specific Role for Stat1 in Protection of the Central Nervous System following Herpes Simplex Virus Corneal Infection

Innate immune deficiencies result in a spectrum of severe clinical outcomes following infection. In particular, there is a strong association between loss of the signal transducer and activator of transcription (Stat) pathway, breach of the blood-brain barrier (BBB), and virus-induced neuropathology...

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Bibliografiske detaljer
Main Authors: Pasieka, Tracy Jo, Cilloniz, Cristian, Carter, Victoria S., Rosato, Pamela, Katze, Michael G., Leib, David A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233176/
https://ncbi.nlm.nih.gov/pubmed/21994441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06032-11
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