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Functional Genomic Analysis of Herpes Simplex Virus Type 1 Counteraction of the Host Innate Response

Herpes simplex virus type 1 (HSV-1) mutants lacking the ICP34.5 gene are severely attenuated in mouse models and have a significant growth defect in confluent mouse embryo fibroblasts. Previously, ICP34.5 was demonstrated to have a crucial role in evading the innate immune response to infection by m...

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Detalhes bibliográficos
Main Authors: Pasieka, Tracy Jo, Baas, Tracey, Carter, Victoria S., Proll, Sean C., Katze, Michael G., Leib, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563739/
https://ncbi.nlm.nih.gov/pubmed/16840339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00333-06
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