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ICP34.5-Dependent and –Independent Activities of Salubrinal in Herpes Simplex Virus-1 Infected Cells
The small molecule salubrinal has antiviral activity against herpes simplex virus-1 (HSV-1) and inhibits dephosphorylation of eIF2α mediated by the HSV-1 protein ICP34.5. We investigated whether salubrinal's activities in infected cells depend on ICP34.5. An ICP34.5 deletion mutant was as sensi...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665023/ https://ncbi.nlm.nih.gov/pubmed/18684481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.06.028 |
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