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Role of Herpes Simplex Virus 1 γ34.5 in the Regulation of IRF3 Signaling
During viral infection, pattern recognition receptors (PRRs) and their associated adaptors recruit TANK-binding kinase 1 (TBK1) to activate interferon regulatory factor 3 (IRF3), resulting in production of type I interferons (IFNs). ICP0 and ICP34.5 are among the proteins encoded by herpes simplex v...
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| Veröffentlicht in: | J Virol |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5686731/ https://ncbi.nlm.nih.gov/pubmed/28904192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01156-17 |
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