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Role of Herpes Simplex Virus 1 γ34.5 in the Regulation of IRF3 Signaling

During viral infection, pattern recognition receptors (PRRs) and their associated adaptors recruit TANK-binding kinase 1 (TBK1) to activate interferon regulatory factor 3 (IRF3), resulting in production of type I interferons (IFNs). ICP0 and ICP34.5 are among the proteins encoded by herpes simplex v...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Manivanh, Richard, Mehrbach, Jesse, Knipe, David M., Leib, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686731/
https://ncbi.nlm.nih.gov/pubmed/28904192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01156-17
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