Chronic Administration of KB-R7943 Induces Up-regulation of Cardiac NCX1

The NCX1 (sodium-calcium exchanger) is up-regulated in human heart failure and in many animal models of heart failure. The potential benefits and risks of therapeutically blocking NCX1 in heart failure and during ischemia-reperfusion are being actively investigated. In this study, we demonstrate tha...

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Hlavní autoři: Xu, Lin, Kappler, Christiana S., Mani, Santhosh K., Shepherd, Neal R., Renaud, Ludivine, Snider, Paige, Conway, Simon J., Menick, Donald R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Membrane Transport, Structure, Function, and Biogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785654/
https://ncbi.nlm.nih.gov/pubmed/19661061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.022855
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