Regulation of Ncx1 Gene Expression in the Normal and Hypertrophic Heart

The Na(+)/Ca(2+) exchanger (NCX1) is crucial in the regulation of [Ca(2+)](i) in the cardiac myocyte. The exchanger is upregulated in cardiac hypertrophy, ischemia, and failure. This upregulation can have an effect on Ca(2+) transients and possibly contribute to diastolic dysfunction and an increase...

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Main Authors: Menick, Donald R., Renaud, Ludivine, Buchholz, Avery, Müller, Joachim G., Zhou, Hongming, Kappler, Christiana S., Kubalak, Steven W., Conway, Simon J., Xu, Lin
格式: Artigo
語言:Inglês
出版: 2007
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096001/
https://ncbi.nlm.nih.gov/pubmed/17446459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1196/annals.1387.058
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