Regulation of Ncx1 Expression: IDENTIFICATION OF REGULATORY ELEMENTS MEDIATING CARDIAC-SPECIFIC EXPRESSION AND UP-REGULATION

The Na(+)-Ca(2+) exchanger (NCX1) is up-regulated in hypertrophy and is often found up-regulated in end-stage heart failure. Studies have shown that the change in its expression contributes to contractile dysfunction. We have previously shown that the 1831-bp Ncx1 H1 (1831Ncx1) promoter directs card...

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Huvudupphovsmän: Xu, Lin, Renaud, Ludivine, Müller, Joachim G., Baicu, Catalin F., Bonnema, D. Dirk, Zhou, Hongming, Kappler, Christiana S., Kubalak, Steven W., Zile, Michael R., Conway, Simon J., Menick, Donald R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096005/
https://ncbi.nlm.nih.gov/pubmed/16966329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M607446200
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