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Transcriptional Pathways and Potential Therapeutic Targets in the Regulation of Ncx1 Expression in Cardiac Hypertrophy and Failure

Changes in cardiac gene expression contribute to the progression of heart failure by affecting cardiomyocyte growth, function, and survival. The Na(+) -Ca(2+) exchanger gene (Ncx1) is upregulated in hypertrophy and is often found elevated in end-stage heart failure. Studies have shown that the chang...

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Detalhes bibliográficos
Main Authors: Menick, Donald R., Li, Mona S., Chernysh, Olga, Renaud, Ludivine, Kimbrough, Denise, Kasiganesan, Harinath, Mani, Santhosh K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624972/
https://ncbi.nlm.nih.gov/pubmed/23224875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4614-4756-6_11
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