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Geminin Stabilizes Cdt1 during Meiosis in Xenopus Oocytes
During the mitotic cell cycle, Geminin can act both as a promoter and inhibitor of initiation of DNA replication. As a promoter, Geminin stabilizes Cdt1 and facilitates its accumulation leading to the assembly of the pre-replication complex on DNA. As an inhibitor, Geminin prevents Cdt1 from loading...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785651/ https://ncbi.nlm.nih.gov/pubmed/19656945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.008854 |
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