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Geminin Stabilizes Cdt1 during Meiosis in Xenopus Oocytes

During the mitotic cell cycle, Geminin can act both as a promoter and inhibitor of initiation of DNA replication. As a promoter, Geminin stabilizes Cdt1 and facilitates its accumulation leading to the assembly of the pre-replication complex on DNA. As an inhibitor, Geminin prevents Cdt1 from loading...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Narasimhachar, Yadushyla, Coué, Martine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785651/
https://ncbi.nlm.nih.gov/pubmed/19656945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.008854
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