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Ischemia Activates the ATF6 Branch of the Endoplasmic Reticulum Stress Response
Stresses that perturb the folding of nascent endoplasmic reticulum (ER) proteins activate the ER stress response. Upon ER stress, ER-associated ATF6 is cleaved; the resulting active cytosolic fragment of ATF6 translocates to the nucleus, binds to ER stress response elements (ERSEs), and induces gene...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785605/ https://ncbi.nlm.nih.gov/pubmed/19622751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.018036 |
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