Coordination of Growth and Endoplasmic Reticulum Stress Signaling by Regulator of Calcineurin 1 (RCAN1), a Novel ATF6-inducible Gene

Exposing cells to conditions that modulate growth can impair endoplasmic reticulum (ER) protein folding, leading to ER stress and activation of the transcription factor, ATF6. ATF6 binds to ER stress response elements in target genes, inducing expression of proteins that enhance the ER protein foldi...

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Detalhes bibliográficos
Main Authors: Belmont, Peter J., Tadimalla, Archana, Chen, Wenqiong J., Martindale, Joshua J., Thuerauf, Donna J., Marcinko, Marie, Gude, Natalie, Sussman, Mark A., Glembotski, Christopher C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376224/
https://ncbi.nlm.nih.gov/pubmed/18319259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709776200
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