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Mesencephalic Astrocyte-derived Neurotrophic Factor Protects the Heart from Ischemic Damage and Is Selectively Secreted upon Sarco/endoplasmic Reticulum Calcium Depletion

The endoplasmic reticulum (ER) stress protein mesencephalic astrocyte-derived neurotrophic factor (MANF) has been reported to protect cells from stress-induced cell death before and after its secretion; however, the conditions under which it is secreted are not known. Accordingly, we examined the me...

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Detalhes bibliográficos
Main Authors: Glembotski, Christopher C., Thuerauf, Donna J., Huang, Chengqun, Vekich, John A., Gottlieb, Roberta A., Doroudgar, Shirin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406674/
https://ncbi.nlm.nih.gov/pubmed/22637475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356345
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