Ischemia Activates the ATF6 Branch of the Endoplasmic Reticulum Stress Response

Stresses that perturb the folding of nascent endoplasmic reticulum (ER) proteins activate the ER stress response. Upon ER stress, ER-associated ATF6 is cleaved; the resulting active cytosolic fragment of ATF6 translocates to the nucleus, binds to ER stress response elements (ERSEs), and induces gene...

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Detaylı Bibliyografya
Asıl Yazarlar: Doroudgar, Shirin, Thuerauf, Donna J., Marcinko, Marie C., Belmont, Peter J., Glembotski, Christopher C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2009
Konular:
Protein Synthesis, Post-Translational Modification, and Degradation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785605/
https://ncbi.nlm.nih.gov/pubmed/19622751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.018036
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