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Ischemia Activates the ATF6 Branch of the Endoplasmic Reticulum Stress Response
Stresses that perturb the folding of nascent endoplasmic reticulum (ER) proteins activate the ER stress response. Upon ER stress, ER-associated ATF6 is cleaved; the resulting active cytosolic fragment of ATF6 translocates to the nucleus, binds to ER stress response elements (ERSEs), and induces gene...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785605/ https://ncbi.nlm.nih.gov/pubmed/19622751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.018036 |
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