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Effects of Moisture Content on the Storage Stability of Dried Lipoplex Formulations

The purpose of this study is to investigate the effects of moisture content on the storage stability of freeze-dried lipoplex formulations. DC-Cholesterol: DOPE (dioleoyl phosphatidylethanolamine) /plasmid DNA lipoplexes were prepared at a 3-to-2 DC-Cholesterol(+) to DNA(−) molar ratio and lyophiliz...

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Detalhes bibliográficos
Main Authors: Yu, Jinxiang, Anchordoquy, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785107/
https://ncbi.nlm.nih.gov/pubmed/19569198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.21846
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