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The Influence of Moisture Content and Temperature on the Long-Term Storage Stability of Freeze-Dried High Concentration Immunoglobulin G (IgG)

High protein concentration products for targeted therapeutic use are often freeze-dried to enhance stability. The long-term storage stability of freeze-dried (FD) plasma-derived Immunoglobulin G (IgG) from moderate to high concentrations (10–200 mg/mL) was assessed. Monomer content, binding activity...

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Bibliografische gegevens
Gepubliceerd in:Pharmaceutics
Hoofdauteurs: Duralliu, Arnold, Matejtschuk, Paul, Stickings, Paul, Hassall, Laura, Tierney, Robert, Williams, Daryl R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238084/
https://ncbi.nlm.nih.gov/pubmed/32230795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12040303
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