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Human Immunoglobulin G2 (IgG2) and IgG4, but Not IgG1 or IgG3, Protect Mice against Cryptococcus neoformans Infection

The encapsulated yeast Cryptococcus neoformans is a significant cause of meningitis and death in patients with AIDS. Some murine monoclonal antibodies (MAbs) against the glucuronoxylomannan (GXM) component of the C. neoformans capsular polysaccharide can prolong the lives of infected mice, while oth...

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書誌詳細
主要な著者: Beenhouwer, David O., Yoo, Esther M., Lai, Chun-Wei, Rocha, Miguel A., Morrison, Sherie L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828574/
https://ncbi.nlm.nih.gov/pubmed/17220317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01161-06
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