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Human Immunoglobulin G2 (IgG2) and IgG4, but Not IgG1 or IgG3, Protect Mice against Cryptococcus neoformans Infection

The encapsulated yeast Cryptococcus neoformans is a significant cause of meningitis and death in patients with AIDS. Some murine monoclonal antibodies (MAbs) against the glucuronoxylomannan (GXM) component of the C. neoformans capsular polysaccharide can prolong the lives of infected mice, while oth...

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Main Authors: Beenhouwer, David O., Yoo, Esther M., Lai, Chun-Wei, Rocha, Miguel A., Morrison, Sherie L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828574/
https://ncbi.nlm.nih.gov/pubmed/17220317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01161-06
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