High Immunoglobulin G2 (IgG2) and Low IgG4 Levels Are Associated with Human Resistance to Plasmodium falciparum Malaria

There is accumulating evidence for a role of immunoglobulin G (IgG) in protection against malarial infection and disease. Only IgG1 and IgG3 are considered cytophilic and protective against P. falciparum, whereas IgG2 and IgG4 were thought to be neither and even to block protective mechanisms. Howev...

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Main Authors: Aucan, Christophe, Traoré, Yves, Tall, François, Nacro, Boubacar, Traoré-Leroux, Thérèse, Fumoux, Francis, Rihet, Pascal
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC97275/
https://ncbi.nlm.nih.gov/pubmed/10678934
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