Human Immunoglobulin G2 (IgG2) and IgG4, but Not IgG1 or IgG3, Protect Mice against Cryptococcus neoformans Infection

The encapsulated yeast Cryptococcus neoformans is a significant cause of meningitis and death in patients with AIDS. Some murine monoclonal antibodies (MAbs) against the glucuronoxylomannan (GXM) component of the C. neoformans capsular polysaccharide can prolong the lives of infected mice, while oth...

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Detalhes bibliográficos
Main Authors: Beenhouwer, David O., Yoo, Esther M., Lai, Chun-Wei, Rocha, Miguel A., Morrison, Sherie L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828574/
https://ncbi.nlm.nih.gov/pubmed/17220317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01161-06
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