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Synergistic Effects of Surfactants and Sugars on Lipoplex Stability During Freeze-drying and Rehydration

The stability of non-viral vectors during freeze-drying has been well-studied, and it has been established that sugars can protect lipoplexes during freeze-drying. However low levels of damage are often observed after freeze-drying, and this damage is more evident in dilute lipoplex preparations. By...

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Detalhes bibliográficos
Main Authors: Yu, Jinxiang, Anchordoquy, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721014/
https://ncbi.nlm.nih.gov/pubmed/18781626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.21564
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