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The Effects of Lipoplex Formulation Variables on the Protein Corona and Comparisons with in vitro Transfection Efficiency

The use of lipoplexes for the intracellular delivery of nucleic acids typically involves the optimization of several parameters that are known to affect delivery. Researchers commonly vary charge ratio, and often incorporate different amounts of helper lipids (e.g., cholesterol) to optimize formulat...

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Detalhes bibliográficos
Main Authors: Betker, Jamie L., Gomez, Joe, Anchordoquy, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795791/
https://ncbi.nlm.nih.gov/pubmed/23920037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.07.024
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