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Non-Additive Effects of Repetitive Administration of Lipoplexes in Immunocompetent Mice
Repetitive administration is routinely used to maintain therapeutic drug levels, but previous studies have documented an accelerated blood clearance of some lipid-based delivery systems under these conditions. To assess the effect of repetitive administration, non-PEGylated lipoplexes (+/− = 0.5) we...
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| Publicado no: | J Pharm Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5657239/ https://ncbi.nlm.nih.gov/pubmed/27887890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2016.11.013 |
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