SM-164: A Novel, Bivalent Smac Mimetic That Induces Apoptosis and Tumor Regression by Concurrent Removal of the Blockade of cIAP-1/2 and XIAP

Antzeko izenburuak

• Potent Bivalent Smac Mimetics: Effect of the Linker on Binding to Inhibitor of Apoptosis Proteins (IAPs) and Anticancer Activity
  nork: Sun, Haiying, et al.
  Argitaratua: (2011)
• Interaction of a Cyclic, Bivalent Smac Mimetic with the X-Linked Inhibitor of Apoptosis Protein,
  nork: Nikolovska-Coleska, Zaneta, et al.
  Argitaratua: (2008)
• Design, Synthesis and Characterization of A Potent, Non-Peptide, Cell-Permeable, Bivalent Smac Mimetic that Concurrently Targets both the BIR2 and BIR3 Domains in XIAP
  nork: Sun, Haiying, et al.
  Argitaratua: (2007)
• Structure-Based Design, Synthesis, Evaluation and Crystallographic Studies of Conformationally Constrained Smac Mimetics as Inhibitors of the X-linked Inhibitor of Apoptosis Protein (XIAP)
  nork: Sun, Haiying, et al.
  Argitaratua: (2008)
• Radiosensitization of head and neck squamous cell carcinoma by a SMAC-mimetic compound, SM-164, requires activation of caspases
  nork: Yang, Jie, et al.
  Argitaratua: (2011)