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Ubiquitination Participates in the Lysosomal Degradation of Na,K-ATPase in Steady-State Conditions

The alveolar epithelial cell (AEC) Na,K-ATPase contributes to vectorial Na(+) transport and plays an important role in keeping the lungs free of edema. We determined, by cell surface labeling with biotin and immunofluorescence, that approximately 30% of total Na,K-ATPase is at the plasma membrane of...

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Bibliografiske detaljer
Main Authors: Lecuona, Emilia, Sun, Haiying, Vohwinkel, Christine, Ciechanover, Aaron, Sznajder, Jacob I.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784405/
https://ncbi.nlm.nih.gov/pubmed/19286978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0365OC
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