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Ouabain-induced Internalization and Lysosomal Degradation of the Na(+)/K(+)-ATPase

Internalization of the Na(+)/K(+)-ATPase (the Na(+) pump) has been studied in the human lung carcinoma cell line H1299 that expresses YFP-tagged α1 from its normal genomic localization. Both real-time imaging and surface biotinylation have demonstrated internalization of α1 induced by ≥100 nm ouabai...

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Bibliographische Detailangaben
Hauptverfasser: Cherniavsky-Lev, Marina, Golani, Ofra, Karlish, Steven J. D., Garty, Haim
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887173/
https://ncbi.nlm.nih.gov/pubmed/24275648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.517003
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