Hyperhomocysteinemia promotes inflammatory monocyte generation and accelerates atherosclerosis in transgenic cystathionine β-synthase deficient mice

BACKGROUND: Hyperhomocysteinemia (HHcy) is an independent risk factor for cardiovascular diseases. Monocytes display inflammatory and resident subsets, and commit to specific functions in atherogenesis. In this study, we examined the hypothesis that HHcy modulates monocyte heterogeneity and leads to...

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Главные авторы: Zhang, Daqing, Jiang, Xiaohua, Fang, Pu, Yan, Yan, Song, Jian, Gupta, Sapna, Schafer, Andrew I., Durante, William, Kruger, Warren D., Yang, Xiaofeng, Wang, Hong
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783582/
https://ncbi.nlm.nih.gov/pubmed/19858416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.866889
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