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Hyperhomocysteinemia promotes inflammatory monocyte generation and accelerates atherosclerosis in transgenic cystathionine β-synthase deficient mice

BACKGROUND: Hyperhomocysteinemia (HHcy) is an independent risk factor for cardiovascular diseases. Monocytes display inflammatory and resident subsets, and commit to specific functions in atherogenesis. In this study, we examined the hypothesis that HHcy modulates monocyte heterogeneity and leads to...

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Detalhes bibliográficos
Main Authors: Zhang, Daqing, Jiang, Xiaohua, Fang, Pu, Yan, Yan, Song, Jian, Gupta, Sapna, Schafer, Andrew I., Durante, William, Kruger, Warren D., Yang, Xiaofeng, Wang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783582/
https://ncbi.nlm.nih.gov/pubmed/19858416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.866889
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