Hyperhomocysteinemia promotes inflammatory monocyte generation and accelerates atherosclerosis in transgenic cystathionine β-synthase deficient mice

BACKGROUND: Hyperhomocysteinemia (HHcy) is an independent risk factor for cardiovascular diseases. Monocytes display inflammatory and resident subsets, and commit to specific functions in atherogenesis. In this study, we examined the hypothesis that HHcy modulates monocyte heterogeneity and leads to...

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Hlavní autoři: Zhang, Daqing, Jiang, Xiaohua, Fang, Pu, Yan, Yan, Song, Jian, Gupta, Sapna, Schafer, Andrew I., Durante, William, Kruger, Warren D., Yang, Xiaofeng, Wang, Hong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783582/
https://ncbi.nlm.nih.gov/pubmed/19858416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.866889
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