Φορτώνει......
Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation
Within the developing pancreas Hepatic Nuclear Factor 6 (HNF6) directly activates the pro-endocrine transcription factor, Ngn3. HNF6 and Ngn3 are each essential for endocrine differentiation and HNF6 is also required for embryonic duct development. Most HNF6(−/−) animals die as neonates, making it d...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783291/ https://ncbi.nlm.nih.gov/pubmed/19766716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2009.09.006 |
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