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Adult pancreatic acinar cells give rise to ducts but not endocrine cells in response to growth factor signaling

Studies in both humans and rodents have found that insulin(+) cells appear within or near ducts of the adult pancreas, particularly following damage or disease, suggesting that these insulin(+) cells arise de novo from ductal epithelium. We have found that insulin(+) cells are continuous with duct c...

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Autors principals: Blaine, Stacy A., Ray, Kevin C., Anunobi, Reginald, Gannon, Maureen A., Washington, Mary K., Means, Anna L.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889602/
https://ncbi.nlm.nih.gov/pubmed/20534672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.048421
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