Pancreatic Ductal Deletion of Hnf1b Disrupts Exocrine Homeostasis, Leads to Pancreatitis, and Facilitates TumorigenesisSummary

Background & Aims: The exocrine pancreas consists of acinar cells that produce digestive enzymes transported to the intestine through a branched ductal epithelium. Chronic pancreatitis is characterized by progressive inflammation, fibrosis, and loss of acinar tissue. These changes of the exocrin...

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Hauptverfasser: Evans Quilichini, Mélanie Fabre, Thassadite Dirami, Aline Stedman, Matias De Vas, Ozge Ozguc, Raymond C. Pasek, Silvia Cereghini, Lucie Morillon, Carmen Guerra, Anne Couvelard, Maureen Gannon, Cécile Haumaitre
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019-01-01
Schriftenreihe:Cellular and Molecular Gastroenterology and Hepatology
Online Zugang:http://www.sciencedirect.com/science/article/pii/S2352345X19300840
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