8-Bromo-cyclic inosine diphosphoribose: towards a selective cyclic ADP-ribose agonist

cADPR (cyclic ADP-ribose) is a universal Ca(2+) mobilizing second messenger. In T-cells cADPR is involved in sustained Ca(2+) release and also in Ca(2+) entry. Potential mechanisms for the latter include either capacitative Ca(2+) entry, secondary to store depletion by cADPR, or direct activation of...

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Detalhes bibliográficos
Main Authors: Kirchberger, Tanja, Moreau, Christelle, Wagner, Gerd K., Fliegert, Ralf, Siebrands, Cornelia C., Nebel, Merle, Schmid, Frederike, Harneit, Angelika, Odoardi, Francesca, Flügel, Alexander, Potter, Barry V. L., Guse, Andreas H.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782309/
https://ncbi.nlm.nih.gov/pubmed/19492987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20082308
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