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Aberrant Cyclization Affords a C-6 Modified Cyclic Adenosine 5′-Diphosphoribose Analogue with Biological Activity in Jurkat T Cells
[Image: see text] Two nicotinamide adenine dinucleotide (NAD(+)) analogues modified at the 6 position of the purine ring were synthesized, and their substrate properties toward Aplysia californica ADP-ribosyl cyclase were investigated. 6-N-Methyl NAD(+) (6-N-methyl nicotinamide adenosine 5′-dinucleo...
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| Main Authors: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2012
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285147/ https://ncbi.nlm.nih.gov/pubmed/22248391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201127y |
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