The Role of Nitric-oxide Synthase in the Regulation of UVB Light-induced Phosphorylation of the α Subunit of Eukaryotic Initiation Factor 2

UV light induces phosphorylation of the α subunit of the eukaryotic initiation factor 2 (eIF2α) and inhibits global protein synthesis. Both eIF2 kinases, protein kinase-like endoplasmic reticulum kinase (PERK) and general control of nonderepressible protein kinase 2 (GCN2), have been shown to phosph...

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Bibliographic Details
Main Authors: Lu, Wei, László, Csaba F., Miao, Zhixin, Chen, Hao, Wu, Shiyong
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Protein Synthesis, Post-Translational Modification, and Degradation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782021/
https://ncbi.nlm.nih.gov/pubmed/19586904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.008821
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