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An Oncogenic Role for the Phosphorylated h-Subunit of Human Translation Initiation Factor eIF3
Dysregulation of protein synthesis has been implicated in oncogenesis through a mechanism whereby “weak” mRNAs encoding proteins involved in cell proliferation are strongly translated when the protein synthesis apparatus is activated. Previous work has determined that many cancer cells contain high...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527115/ https://ncbi.nlm.nih.gov/pubmed/18544531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800956200 |
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