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Structure of a Viral Cap-independent Translation Element That Functions via High Affinity Binding to the eIF4E Subunit of eIF4F

RNAs of many positive strand RNA viruses lack a 5′ cap structure and instead rely on cap-independent translation elements (CITEs) to facilitate efficient translation initiation. The mechanisms by which these RNAs recruit ribosomes are poorly understood, and for many viruses the CITE is unknown. Here...

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Detalhes bibliográficos
Main Authors: Wang, Zhaohui, Treder, Krzysztof, Miller, W. Allen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682867/
https://ncbi.nlm.nih.gov/pubmed/19276085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808841200
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