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Ablation of Ventricular Myosin Regulatory Light Chain Phosphorylation in Mice Causes Cardiac Dysfunction in Situ and Affects Neighboring Myofilament Protein Phosphorylation

There is little direct evidence on the role of myosin regulatory light chain phosphorylation in ejecting hearts. In studies reported here we determined the effects of regulatory light chain (RLC) phosphorylation on in situ cardiac systolic mechanics and in vitro myofibrillar mechanics. We compared d...

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主要な著者: Scruggs, Sarah B., Hinken, Aaron C., Thawornkaiwong, Ariyaporn, Robbins, Jeffrey, Walker, Lori A., de Tombe, Pieter P., Geenen, David L., Buttrick, Peter M., Solaro, R. John
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2009
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643522/
https://ncbi.nlm.nih.gov/pubmed/19106098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807414200
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