Ablation of Ventricular Myosin Regulatory Light Chain Phosphorylation in Mice Causes Cardiac Dysfunction in Situ and Affects Neighboring Myofilament Protein Phosphorylation

There is little direct evidence on the role of myosin regulatory light chain phosphorylation in ejecting hearts. In studies reported here we determined the effects of regulatory light chain (RLC) phosphorylation on in situ cardiac systolic mechanics and in vitro myofibrillar mechanics. We compared d...

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מידע ביבליוגרפי
Main Authors: Scruggs, Sarah B., Hinken, Aaron C., Thawornkaiwong, Ariyaporn, Robbins, Jeffrey, Walker, Lori A., de Tombe, Pieter P., Geenen, David L., Buttrick, Peter M., Solaro, R. John
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2009
נושאים:
Protein Synthesis, Post-Translational Modification, and Degradation
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643522/
https://ncbi.nlm.nih.gov/pubmed/19106098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807414200
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