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Increasing the coverage of a metapopulation consensus genome by iterative read mapping and assembly

Motivation: Most microbial species can not be cultured in the laboratory. Metagenomic sequencing may still yield a complete genome if the sequenced community is enriched and the sequencing coverage is high. However, the complexity in a natural population may cause the enrichment culture to contain m...

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Detalhes bibliográficos
Main Authors: Dutilh, Bas E., Huynen, Martijn A., Strous, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781756/
https://ncbi.nlm.nih.gov/pubmed/19542148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp377
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