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Improving draft assemblies by iterative mapping and assembly of short reads to eliminate gaps

Advances in sequencing technology allow genomes to be sequenced at vastly decreased costs. However, the assembled data frequently are highly fragmented with many gaps. We present a practical approach that uses Illumina sequences to improve draft genome assemblies by aligning sequences against contig...

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Detalhes bibliográficos
Main Authors: Tsai, Isheng J, Otto, Thomas D, Berriman, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884544/
https://ncbi.nlm.nih.gov/pubmed/20388197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-4-r41
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