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Improving draft assemblies by iterative mapping and assembly of short reads to eliminate gaps
Advances in sequencing technology allow genomes to be sequenced at vastly decreased costs. However, the assembled data frequently are highly fragmented with many gaps. We present a practical approach that uses Illumina sequences to improve draft genome assemblies by aligning sequences against contig...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2884544/ https://ncbi.nlm.nih.gov/pubmed/20388197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-4-r41 |
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