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Analysis of the cytoplasmic interaction between polycystin-1 and polycystin-2
Autosomal dominant polycystic kidney disease (ADPKD) arises following mutations of either Pkd1 or Pkd2. The proteins these genes encode, polycystin-1 (PC1) and polycystin-2 (PC2), form a signaling complex using direct intermolecular interactions. Two distinct domains in the C-terminal tail of PC2 ha...
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Päätekijät: | , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
American Physiological Society
2009
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781345/ https://ncbi.nlm.nih.gov/pubmed/19726544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00412.2009 |
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