Analysis of the cytoplasmic interaction between polycystin-1 and polycystin-2

Autosomal dominant polycystic kidney disease (ADPKD) arises following mutations of either Pkd1 or Pkd2. The proteins these genes encode, polycystin-1 (PC1) and polycystin-2 (PC2), form a signaling complex using direct intermolecular interactions. Two distinct domains in the C-terminal tail of PC2 ha...

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Main Authors: Casuscelli, Jozefina, Schmidt, Stefan, DeGray, Brenda, Petri, Edward T., Ćelić, Andjelka, Folta-Stogniew, Ewa, Ehrlich, Barbara E., Boggon, Titus J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781345/
https://ncbi.nlm.nih.gov/pubmed/19726544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00412.2009
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