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DISCRETE PROTEOLYSIS OF NEURONAL CALCIUM SENSOR 1 (NCS-1) BY μ-CALPAIN DISRUPTS CALCIUM BINDING
Neuronal Calcium Sensor-1 (NCS-1) is a high-affinity, low-capacity Ca(2+)-binding protein expressed in many cell types. We previously showed that NCS-1 interacts with inositol 1,4,5-trisphosphate receptor (InsP3R) and modulates Ca(2+)-signaling by enhancing InsP3-dependent InsP3R channel activity an...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2763996/ https://ncbi.nlm.nih.gov/pubmed/19732951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2009.08.002 |
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