DISCRETE PROTEOLYSIS OF NEURONAL CALCIUM SENSOR 1 (NCS-1) BY μ-CALPAIN DISRUPTS CALCIUM BINDING

Neuronal Calcium Sensor-1 (NCS-1) is a high-affinity, low-capacity Ca(2+)-binding protein expressed in many cell types. We previously showed that NCS-1 interacts with inositol 1,4,5-trisphosphate receptor (InsP3R) and modulates Ca(2+)-signaling by enhancing InsP3-dependent InsP3R channel activity an...

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Päätekijät: Blachford, Courtney, Ćelić, Andjelka, Petri, Edward T., Ehrlich, Barbara E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763996/
https://ncbi.nlm.nih.gov/pubmed/19732951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2009.08.002
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