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Conformational selection and induced fit mechanism underlie specificity in noncovalent interactions with ubiquitin

Noncovalent binding interactions between proteins are the central physicochemical phenomenon underlying biological signaling and functional control on the molecular level. Here, we perform an extensive structural analysis of a large set of bound and unbound ubiquitin conformers and study the level o...

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Sonraí Bibleagrafaíochta
Main Authors: Wlodarski, Tomasz, Zagrovic, Bojan
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780739/
https://ncbi.nlm.nih.gov/pubmed/19887638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906966106
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