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High TCL1 levels are a marker of B-cell receptor pathway responsiveness and adverse outcome in chronic lymphocytic leukemia

Although activation of the B-cell receptor (BCR) signaling pathway is implicated in the pathogenesis of chronic lymphocytic leukemia (CLL), its clinical impact and the molecular correlates of such response are not clearly defined. T-cell leukemia 1 (TCL1), the AKT modulator and proto-oncogene, is di...

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Bibliografski detalji
Glavni autori: Herling, Marco, Patel, Kaushali A., Weit, Nicole, Lilienthal, Nils, Hallek, Michael, Keating, Michael J., Jones, Dan
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780304/
https://ncbi.nlm.nih.gov/pubmed/19770358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-208256
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