Accelerated progression of chronic lymphocytic leukemia in Eμ-TCL1 mice expressing catalytically inactive RAG1

Chronic lymphocytic leukemia (CLL) is a prevalent B-cell neoplasia that is often preceded by a more benign monoclonal CD5(+) B-cell lymphocytosis. We previously generated transgenic mice expressing catalytically inactive RAG1 (dominant-negative recombination activating gene 1 [dnRAG1] mice) that dev...

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Detalhes bibliográficos
Main Authors: Nganga, Vincent K., Palmer, Victoria L., Naushad, Hina, Kassmeier, Michele D., Anderson, Dirk K., Perry, Greg A., Schabla, Nathan M., Swanson, Patrick C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700393/
https://ncbi.nlm.nih.gov/pubmed/23502221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-08-446732
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