Accumulation of B1-like B cells in transgenic mice over-expressing catalytically inactive RAG1 in the periphery

During their development, B lymphocytes undergo V(D)J recombination events and selection processes that, if successfully completed, produce mature B cells expressing a non-self-reactive B-cell receptor (BCR). Primary V(D)J rearrangements yield self-reactive B cells at high frequency, triggering atte...

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Detalhes bibliográficos
Main Authors: Hassaballa, Ashraf E, Palmer, Victoria L, Anderson, Dirk K, Kassmeier, Michele D, Nganga, Vincent K, Parks, Kevin W, Volkmer, Dustin L, Perry, Greg A, Swanson, Patrick C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230800/
https://ncbi.nlm.nih.gov/pubmed/22044391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03509.x
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