Cd1d regulates B cell development but not B cell accumulation and IL10 production in mice with pathologic CD5(+) B cell expansion

BACKGROUND: CD1d is a widely expressed lipid antigen presenting molecule required for CD1d-restricted invariant natural killer T (iNKT) cell development. Elevated CD1d expression is detected in CD5(+) IL10-producing B cells, called B10 B cells, and is correlated with poorer prognosis in chronic lymp...

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Publicado en:BMC Immunol
Autores principales: Palmer, Victoria L., Nganga, Vincent K., Rothermund, Mary E., Perry, Greg A., Swanson, Patrick C.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632344/
https://ncbi.nlm.nih.gov/pubmed/26537916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-015-0130-z
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